ALS pathology investigated by UCF/Hesperos Researchers Utilizing a Human-on-a-Chip® model

als

UCF/HESPEROS RESEARCHERS UTILIZE HUMAN-ON-A-CHIP® APPROACH TO MODEL ALS PATHOLOGY Key Findings Data supports use of functional neuromuscular junction (NMJ) system to evaluate amyotrophic lateral sclerosis pathology  First study to validate the use of Deanna protocol in a human system as a strategy for treating ALS  Press Release  ORLANDO, Fla. — The Hybrid Systems Lab at … Read more

Hesperos demonstrates innovative Human-on-a-Chip® approach to modeling innate immune system response following tissue damage and acute inflammation

hesperos

— New publication in Advanced Science validates potential use in evaluating certain immune responses in drug discovery and systemic diseases, including Coronavirus Disease 2019 (COVID-19)— — Hesperos’ immune system-on-a-chip features recirculating immune cells with the key organ mimics heart, skeletal muscle and liver ORLANDO, Fla. – June 2, 2020 — Hesperos Inc., pioneers of the … Read more

Preclinical Stages of Alzheimer’s Disease and Mild Cognitive Impairment modeled with HUMAN-ON-A-CHIP®

Hesperos

PRECLINICAL STAGES OF ALZHEIMER’S DISEASE AND MILD COGNITIVE IMPAIRMENT MODELED WITH HESPEROS HUMAN-ON-A-CHIP® SYSTEM — Peer-reviewed publication in Alzheimer’s & Dementia: Translational Research & Clinical Interventions validates potential of drug discovery platform and ability to study early stages of disease pathology — ORLANDO, Fla. – May 28, 2020 – Hesperos Inc., pioneers of the Human-on-a-Chip® … Read more

Human-on-a-chip for Rare Diseases discussion

Human-on-a-Chip

HUMAN-ON-A-CHIP FOR RARE DISEASES DISCUSSION In our latest publication, UCF & Hesperos researchers discuss how Human-on-a-chip systems can be used to address the unique challenges facing rare diseases. Researchers cite that rare diseases are “limited by the high cost of research and low target population.” Further Discussion of Human-on-a-chip® technology Researchers further discuss how “Human-on-a-chip … Read more

NIH Director Features HESPEROS BODY-ON-A-CHIP DEVICE for predicting CANCER DRUG RESPONSES

Dr. Francis Collins, director of The National Institutes of Health, recently featured Hesperos technology on his blog. In the post, Dr. Collins reviews a published study where Hesperos researchers investigated and treated several cancer lines with existing chemotherapeutics.  The study both treated the cancer while reproducing known toxic effects of specific drugs and their more … Read more

Hesperos Human-on-a-Chip Technology Awarded First Phase of $3.8 Million Milestone-based NIH Grant to Study Opiate Overdoses in Collaboration With UCF

Hesperos

Hesperos, Inc., (www.hesperosinc.com) announced today the University of Central Florida (UCF) received the first phase of a $3.8 million milestone-based National Institutes of Health (NIH) grant for research involving the company’s human-on-a-chip system. “We are grateful to have funding to support research in an area that represents such a large and growing need,” said Dr. … Read more

Human-on-a-Chip Predicts In Vivo Results Based on In Vitro Model for the first time

human-on-a-chip

HUMAN-ON-A-CHIP PREDICTS IN VIVO RESULTS BASED ON IN VITRO MODEL FOR THE FIRST TIME Hesperos’ integrated heart-liver Human-on-a-Chip® shown to correctly determine cardiotoxic mechanisms preclinically and replicate results seen in in vivo studies (ORLANDO, Fla.) — Hesperos Inc., pioneers of the “human-on-a-chip” in vitro system has announced the use of its innovative multi-organ model to successfully measure the concentration and metabolism of two known … Read more

Hesperos’ Models Under Consideration to Address Opiod Crisis

hesperos

The interest in our human-on-a-chip model continues to grow.  Last week we brought our systems to the National Center for Translational Science (NCATS) at the NIH in Washington, D.C. to perform a real-time demo using live cells. Hesperos, Inc. is the first company spun out from the Tissue Chip Program at NCATS. In attendance were … Read more