Toxicity testing

Dr. Hickman Presents Human-on-a-Chip® at Florida Simulation Summit 2020

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human-on-a-chip

Presentation Highlights

This is a company overview presentation given by Dr. James Hickman at this years Florida Simulation Summit 2020 in October.  Learn more about the technology and exciting path ahead. Key highlights from the presentation include:

  • A brief history of Hesperos
  • How the Human-on-a-Chip technology works and the current state of the technology
  • Key applications and path forward

Human-on-a-Chip®

Functional in vitro models that accurately predict how new drug candidates will impact the human body – something that has previously required animal testing or human clinical trials to determine.

What’s on each Chip?

Systemic toxicology models with interlinked organs, including: heart, liver, lung, brain, skin, muscle, GI tract, kidney, pancreas, endocrine, bone marrow and the neuromuscular junction in a serum free, recirculating medium utilizing a pumpless platform.

Human-on-a-chip Model Enables Simultaneous Testing of Cancer Drug Efficacy and Off-Target Toxicity to Enable Determination of Therapeutic Index

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hesperos

In vitro multi-organ system by Hesperos, Inc. realistically replicates the responses of cancer treatments and has potential to inform treatment decisions. ORLANDO, FLA – June 19, 2019 — A reconfigurable “body-on-a-chip” model could transform drug development by simultaneously measuring compound efficacy and toxicity, for both target cells and other organs, such as the heart and … Read more

Hesperos’ multi-organ Human-on-a-Chip System Found Effective for Long-Term Toxicology Testing

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Hesperos

HESPEROS’ MULTI-ORGAN “HUMAN-ON-A-CHIP” SYSTEM FOUND EFFECTIVE FOR LONG-TERM TOXICOLOGY TESTING Collaboration between L’Oreal, Hesperos and UCF results in further reduction in reliance on animal testing in drug and cosmetics development (ORLANDO, Fla.) The replacement of animals as test subjects is one step closer to reality with the successful testing of multi-organ “human-on-a-chip” models to recapitulate … Read more

Hesperos To Create Multi-Organ Human-On-A-Chip Model to Test Alzheimer’s Drugs

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Hesperos

Hesperos, Inc., announced today the receipt of a NIH Phase I Small Business Innovation Research (SBIR) grant from the National Institutes of Health (NIH) National Institute on Aging (NIA) to help create a new multi-organ “human-on-a-chip” model that can realistically mimic the biology of Alzheimer’s Disease (AD) and the effects of potential new therapies under … Read more